Pregabalin Vs Gabapentin – Which One Is Stronger?
When it comes to managing nerve-related conditions such as neuropathic pain, anxiety disorders, and seizures, two medications that often come up are Pregabalin and Gabapentin. Both drugs work by affecting the way the brain and nervous system process pain. However, while they share similarities, there are key differences between them. Many times, the question is, is Pregabalin stronger than Gabapentin? Well, in terms of strength, efficacy, and side effects there can be differences in both. So, to evaluate which one takes the lead, let’s unfold the specs.
What Are Pregabalin and Gabapentin?
Pregabalin and Gabapentin are both strong painkillers and are often prescribed to treat similar conditions. Gabapentin is often used to treat seizures, neuropathic pain, and restless legs syndrome. However, Pregabalin is used for a broader range of conditions, including generalized anxiety disorder (GAD), fibromyalgia, and even to manage seizures along with nerve pain.
Surprisingly, in Pregabalin vs Gabapentin we can find out a similar structure and mechanism of action. These are designed to block specific calcium channels and divert the pain transmission in the body. It results in relaxing the nerves and sedation as well. Let’s have a closer look at how these are similar and different. Pregabalin for sale, buy pregabalin online in the UK.
Strength and Efficacy
One of the most common questions surrounding these two medications is which one is stronger. Generally, Pregabalin 300 mg is considered stronger than Gabapentin in terms of potency. There are certain reasons for this strength:
- Pregabalin comes with higher bioavailability, meaning it lasts for longer in the body offering extended results as compared to Gabapentin.
- A smaller dose of Pregabalin offers equivalent results to a higher dose of Gabapentin. You need to take fewer doses of Pregabalin throughout the day.
- Pregabalin acts faster than Gabapentin, providing quicker relief for conditions like anxiety and pain. Gabapentin, in contrast, may take a bit longer to reach full effectiveness.
Side Effects and Tolerability
While Pregabalin is stronger and more potent, this also means it can come with a higher risk of side effects. However, for some people it’s possible to tolerate Gabapentin easily which makes it comfortable for the majority. Being the similar medications, these two share a similar set of side effects that includes:
- Dizziness
- Drowsiness
- Nausea
- Allergic reactions
- Sedation
- Lack of muscle coordination
However, Pregabalin 300 mg tends to cause more significant side effects in some patients, such as weight gain and memory problems.
| Feature | Pregabalin | Gabapentin |
| Primary Uses | Neuropathic pain, generalized anxiety disorder (GAD), fibromyalgia, seizures | Neuropathic pain, seizures, restless legs syndrome |
| Bioavailability | 90% | 60% |
| Potency | More potent, effective at lower doses | Less potent, often requires higher doses |
| Dosing Frequency | 1-3 times a day | 3 times a day |
| Onset of Action | Faster (quicker relief) | Slower onset |
| Half-life | 6 hours | 5-7 hours |
| Side Effects | Dizziness, drowsiness, weight gain, memory issues, swelling | Dizziness, drowsiness, fatigue, swelling |
| Tolerability | Can be less tolerable in some patients | Better tolerated |
| Cost | More expensive | More affordable |
| Withdrawal Symptoms | Can be more intense if stopped abruptly | Milder withdrawal symptoms |
| Approved for Anxiety | Yes | No |
Wrap Up!
In the battle of Pregabalin vs. Gabapentin, Pregabalin is generally stronger and faster-acting, with higher bioavailability and greater potency. However, its increased strength may come at the cost of a higher risk of side effects. Gabapentin, while less potent, may be a better option for individuals who require a lower dose or who are more sensitive to the side effects of medication. However, the selection among both medicines is entirely based on a patient’s condition and need.
No matter if you are taking Pregabalin 300 mg or Gabapentin 300 mg, it’s best to buy these online in the UK from a tested source. At Sleeping Tabs, we are offering you the best quality medicines with an assurance to enjoy effective results. So, but right and be safe.
Also read how pregabalin helps treating nerve pain.
FAQs
Is Pregabalin stronger than Gabapentin?
Generally, yes, Pregabalin is stronger than Gabapentin as it offers faster onset and longer half-life. However, at the same time it has some risk of addiction or side effects as well.
Can I take Pregabalin and Gabapentin together?
No, these two are the identical medicines and should not be taken together until carefully prescribed by the doctor. Taking these two in combination mostly risk the overdose and trigger side effect reactions.
How long does it take for Pregabalin to start working?
Pregabalin generally starts working within a few hours, with its peak effects occurring within 2-3 hours. It may take a few days to notice full benefits, especially for conditions like anxiety or fibromyalgia. Read here for more detail on how long does pregabalin takes to work!
Can Pregabalin or Gabapentin help with anxiety?
Pregabalin is approved for the treatment of generalized anxiety disorder (GAD), whereas Gabapentin is not. Also read how pregabalin takes to work for anxiety!